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While this mechanism underlies their metabolic benefits, it also predisposes patients to gastrointestinal side effects such as nausea, vomiting, and abdominal pain, which are among the most frequently reported adverse events with these medications [7]

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Additionally, in mouse models of diabetes, chronic treatment with GLP-1R agonists for 4 to 10 wk significantly increased the number of progenitor cells or doublecortin (DCX)-positive young neurons in the dentate gyrus