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And among these substances, there is a particularly prominent one, nicotine, which apart from being carcinogenic and able to cause immediate toxic effects (rise in cardiac frequency and blood pressure, and even acute intoxication syndromes), is all by itself responsible for cigarette dependency and the difficulty to quit smoking

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During the course of the clip, she could be seen holding two cigarettes in her hand and in another snippet, was joined by friends as they all had a smoke In August, Lady Gaga and Bruno Mars collaborated on the track Die With A Smile - and in the cover art, the pair stood together in coordinating ensembles while she held a cigarette in her hand And during the music video, Gaga had a cigarette in her mouth as she played the piano and belted out lyrics