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ERK1/2 & VEGFR2 Mechanism Musculoskeletal Scoping Review (PMC, 2025) A 2025 scoping review confirmed BPC-157 activates VEGFR2 and drives nitric oxide synthesis via the Akt-eNOS axis, promoting angiogenesis, fibroblast activity, and neuromuscular stabilisation

Results showed: Significantly faster healing compared to controls Improved biomechanical properties of healed tendons Better collagen fiber organization Enhanced tensile strength Follow-up studies confirmed these findings and demonstrated that BPC-157 stimulated tendon cell (tenocyte) proliferation and migration in vitro

During: a small cannula is placed (usually in the arm)

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